New Research Shows Mesothelioma Surgery Has the Biggest Impact in the Most Severe Cases, According to Surviving Mesothelioma

P/D Surgery for Malignant Mesothelioma

Sickest Patients May Benefit Most from Mesothelioma Surgery

Non-epithelioid histology and patients with large pathological tumor volume demonstrated greater improvement in global health...

In a new study including 114 malignant pleural mesothelioma patients, scientists in Chicago found that those with rarer and larger mesothelioma tumors tended to experience the most improvement in their symptoms after P/D surgery. Surviving Mesothelioma has the details.Click here to read the full article now.

Researchers at the University of Chicago and Loyola University conducted health assessments on patients before mesothelioma surgery, then again at 1, 4-5, 7-8, and 10-11 months afterward.

“Non-epithelioid histology and patients with large pathological tumor volume demonstrated greater improvement in global health, function and symptoms domains following pleurectomy with decortication,” writes surgeon and lead researcher, Wickii Vigneswaran, MD, of Loyola University.

According to the study, patients with the more common epithelioid subtype of mesothelioma and those with smaller tumors reported a lower quality of life a month after P/D surgery than they had at baseline, although they did steadily improve.

“The take-home message here is that, although P/D surgery may extend survival, it may not be the best choice for every mesothelioma patient, particularly in cases where symptoms are being kept in check by other means,” says Alex Strauss, Managing Editor for Surviving Mesothelioma.

To read the details of the new P/D surgery study and more recent research on lung-sparing mesothelioma surgery, see Sickest Mesothelioma Patients May Benefit Most from P/D Surgery, now available on the Surviving Mesothelioma website.

Vigneswaran, WT, et al, “Influence of Pleurectomy and Decortication in Health-Related Quality of Life Among Patients with Malignant Pleural Mesothelioma”, September 25, 2017, World Journal of Surgery, Epub ahead of print,

For more than a decade, Surviving Mesothelioma has brought readers the most important and ground-breaking news on the causes, diagnosis and treatment of mesothelioma. All Surviving Mesothelioma news is gathered and reported directly from the peer-reviewed medical literature. Written for patients and their loved ones, Surviving Mesothelioma news helps families make more informed decisions.

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